Pharmacokinetic Study and Tissue Distribution of Lorlatinib in Mouse Serum and Tissue Samples by Liquid Chromatography-Mass Spectrometry

Figure 2

Chromatograms of serum and tissues: (a) blank serum, (b) blank lung, (c) blank serum spiked with lorlatinib and IS, (d) serum sample obtained at 30 min after oral administration of lorlatinib, and (e) lung sample obtained at 30 min after oral administration of lorlatinib. 1: lorlatinib; 2: IS.

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