The Application of CA and PCA to the Evaluation of Lipophilicity and Physicochemical Properties of Tetracyclic Diazaphenothiazine Derivatives

Table 3

Values of lipophilicity parameters of 5-methyl-12 (H)-quin [3,4-b] pyrido [2,3-e] [1, 4] thiazine salts 1–11 obtained using computer methods.

No.	AClogP	ALOGP	ALOGPs	miLogP	MLOGP	XLOGP2	XLOGP3
1	2.74	3.35	−0.90	−0.13	1.38	2.69	3.27
2	3.35	4.33	−0.12	1.02	2.02	3.58	4.30
3	3.44	4.09	−0.30	0.83	2.02	3.49	3.96
4	3.44	4.22	−0.15	0.89	1.90	3.40	4.23
5	3.28	3.93	−0.42	0.38	1.78	2.94	3.71
6	3.76	4.45	−0.13	1.30	2.14	3.85	3.96
7	3.76	4.70	0.01	1.27	2.14	3.63	4.60
8	3.59	4.42	−0.28	0.75	2.02	3.17	4.07
9	3.06	3.83	−0.75	0.25	1.63	2.92	3.64
10	3.11	3.87	−0.58	0.27	1.91	3.34	3.58
11	2.65	2.81	−1.16	−0.33	1.38	2.61	2.94