Chemical Investigation of a Biologically Active Schinus molle L. Leaf Extract

Table 2

SML1 fractions obtained by LPLC and tested on human leukaemia cells (HL-60).

LPLC fractions	Yields (%)	EC50 (μg/mL)
F1	23.7	6.5 ± 0.9
F2	30.3	12.8 ± 1.3
F3	3.6	5.5 ± 0.4
F4	1.9	3.8 ± 0.3
F5	1.7	5.4 ± 0.3
F6	4.7	4.1 ± 0.3
F7	11.4	143.5 ± 34.1
F8	4.6	37.9 ± 10.7

Cytotoxic activity was expressed by EC₅₀ (mean values ± SEM). Vinblastine was used as positive control (EC₅₀ = 12.2 ± 1.3 nM).