Degradation Characteristics of a Novel PAF Receptor Antagonist, SY0916, in Aqueous Solution

Table 2

¹H and ¹³C chemical shifts (ppm) and ¹H coupling data of D1 from NMR and of D2 from LC-SPE-NMR.

Position	D1				D2
	δH (ppm)	δC (ppm)	HSQC	HMBC	δH (ppm)	δC (ppm)	HSQC	HMBC
1	7.64 (d, J = 16.1 Hz)	144.03	H-1	H-2′(6′), H-2	7.55 (d, J = 16.3 Hz)	143.12	H-1	H-2′(6′)
2	7.11 (d, J = 16.1 Hz)	125.71	H-2	H-1	6.81 (d, J = 16.3 Hz)	128.07	H-2	—
3	—	191.47	—	H-1, H-2, H-4, H-5 (Ha), H-5 (Hb)	—	201.20	—	H-1, H-2, H-4, H-5
4	6.73 (dd, J = 17.5 Hz, 10.7 Hz)	136.58	H-4	H-5 (Ha)	2.87 (t, J = 6.1 Hz)	44.10	H-4	H-5
5	6.37 (Ha, dd, J = 17.5 Hz, 1.2 Hz)	129.86	H-5 (Ha)	—	3.84 (t, J = 6.1 Hz)	58.50	H-5	H-4
	5.89 (Hb, dd, J = 10.7 Hz, 1.2 Hz)		H-5 (Hb)
1′	—	134.85	—	H-2, H-3′(5′)	—	134.79	—	H-3′(5′)
2′	7.62–7.60 (m)	131.05	H-2′ (H-6′)	H-1	7.61-7.58 (m)	130.93	H-2′ (H-6′)	H-1, H-3′(5′)
3′	7.37-7.36 (m)	130.24	H-3′ (H-5′)	—	7.37 (d, J = 8.5 Hz)	130.23	H-3′ (H-5′)	H-2′(6′)
4′	—	137.54	—	H-2′(6′), H-3′(5′)	-	137.41	-	H-2′(6′)
5′	7.37-7.36 (m)	130.24	H-5′ (H-3′)	—	7.37 (d, J = 8.5 Hz)	130.23	H-5′ (H-3′)	H-2′(6′)
6′	7.62–7.60 (m)	131.05	H-6′ (H-2′)	H-1	7.61-7.58 (m)	130.93	H-6′ (H-2′)	H-1, H-3′(5′)