Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study

<div>Representative MRM chromatogram of 5-ISMN and IS (<sup>13</sup>C<sub>6</sub>-5-ISMN, 1000 ng/mL). (a) Blank plasma, (b) blank plasma spiked with IS, (c) LLOQ plasma sample, and (d) unknown clinical plasma sample.</div>

Journal of Analytical Methods in Chemistry

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Figure 3: Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study 

Figure 3 | Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study 