Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study

<div>The mean concentration-time curves of reference and test drugs in Chinese healthy subjects after a single dose of the 20 mg 5-ISMN tablet in fasting condition (<i>n</i> = 28) (a) and fed condition (<i>n</i> = 28) (b).</div>

Journal of Analytical Methods in Chemistry

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Figure 4

Figure 4: Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study 

Figure 4 | Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study 