Effects of the Salt-Processing Method on the Pharmacokinetics and Tissue Distribution of Orally Administered Morinda officinalis How. Extract

Table 2

Calibration curves and LLOQs of components in rat plasma and tissues.

	Components	Calibration curves	r^2	Range (μg/mL)	LLOQ (μg/mL)
Plasma	Rubiadin	Y = 3.32809X + 0.40361	r^2 = 0.9936	1.2∼950	1.2
	Rubiadin 1-methyl ether	Y = 1.08619X + 1.03779	r^2 = 0.9919	1.3∼1020	1.3
	Monotropein	Y = 0.0256X − 0.0026	r^2 = 0.9943	0.047∼37.5	0.047
Liver	Rubiadin	Y = 4.4365X + 0.629	r^2 = 0.9928	0.07∼6.18	0.07
	Rubiadin 1-methyl ether	Y = 5.0622X + 0.7667	r^2 = 0.9911	0.05∼4.66	0.05
	Monotropein	Y = 0.0315X − 0.0741	r^2 = 0.9915	0.47∼37.5	0.47
Small intestine	Rubiadin	Y = 3.4909X − 2.2398	r^2 = 0.9907	0.07∼12.375	0.07
	Rubiadin 1-methyl ether	Y = 6.4061X − 0.1149	r^2 = 0.9926	0.092∼9.2	0.092
	Monotropein	Y = 0.0214X − 0.0251	r^2 = 0.9969	0.47∼37.5	0.47
Kidney	Rubiadin	Y = 3.5819X − 0.9479	r^2 = 0.9938	0.07∼6.18	0.07
	Rubiadin 1-methyl ether	Y = 5.3299X − 0.6431	r^2 = 0.9968	0.05∼4.66	0.05
	Monotropein	Y = 0.0333X − 0.0156	r^2 = 0.9997	0.47∼37.5	0.47
Lung	Rubiadin	Y = 4.4389X − 0.7058	r^2 = 0.9966	0.07∼6.18	0.07
	Rubiadin 1-methyl ether	Y = 8.7095X − 2.3863	r^2 = 0.9919	0.05∼4.66	0.05