Research Article

Effects of the Salt-Processing Method on the Pharmacokinetics and Tissue Distribution of Orally Administered Morinda officinalis How. Extract

Table 5

Extraction recoveries in rat plasma and tissues (n = 5).

MatrixCompoundsConc. (μg/mL)Recoveries (%)RSD (%)

PlasmaRubiadin3.688.347.03
50.695.081.89
712.596.390.93
Rubiadin 1-methyl ether3.981.893.24
54.693.423.13
76594.051.44
Monotropein0.1495.513.66
291.973.88
28.197.601.10

Small intestineRubiadin0.2185.243.91
0.9891.094.05
4.6396.211.15
Rubiadin 1-methyl ether0.1592.442.20
0.7291.398.03
3.4986.973.60
Monotropein1.4198.271.83
6.298.641.03
28.1392.950.02

LiverRubiadin0.2189.372.15
0.9888.981.13
4.6394.162.78
Rubiadin 1-methyl ether0.1588.897.21
0.7285.973.28
3.4990.841.87
Monotropein1.4197.073.25
6.297.671.61
28.1396.410.91

KidneyRubiadin0.2188.734.56
0.9882.078.44
4.6393.594.07
Rubiadin 1-methyl ether0.1588.894.26
0.7293.616.61
3.4989.983.55
Monotropein1.4193.954.96
6.293.414.95
28.1394.470.87

LungRubiadin0.2180.632.46
0.9880.076.59
4.6383.971.47
Rubiadin 1-methyl ether0.1591.113.30
0.7286.675.77
3.4988.965.08