Research Article
An Analytical Perspective on Determination of Free Base Nicotine in E-Liquids
Table 6
Comparison between free base nicotine in e-liquids by dilution approach (HH) and by without-dilution approach (1H NMR) (e-liquids without dilution).
| | e-Liquid flavor (80 mg/mL) | e-Liquid category | Mean % free base nicotine by Henderson–Hasselbalch equation (with dilution) | Mean % free base nicotine by 1H NMR (without dilution) | % deviation |
| | Maui menthol | Menthol | 94.99 | 69.41 | 26.93 | | Element tobacco | Tobacco | 83.3 | 73.6 | 11.64 | | Motley brew | Fruit | 83.01 | 74.4 | 10.37 | | Milkman milky cloud | Sweet | 82.45 | 75.8 | 8.07 | | Hazelnut coffee | Coffee | 96.45 | 92.88 | 3.70 |
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