Research Article

Development and Validation of LC-MS/MS for Analyzing Potential Genotoxic Impurities in Pantoprazole Starting Materials

Table 2

MS fragment pathways and quantitative ions of PGIs.

No.CodeMRM (m/z)MS fragment pathways

1Impurity Cm/z 160.2 ⟶ m/z 93.0
2Impurity Dm/z 202.2 ⟶ m/z 160.0
3Impurity Em/z 175.1 ⟶ m/z 108.0
4Impurity Fm/z 247.1 ⟶ m/z 187.0
5Impurity Gm/z 205.1 ⟶ m/z 137.0
6Impurity Hm/z 110.0 ⟶ m/z 65.0