Journal of Analytical Methods in Chemistry / 2020 / Article / Tab 2 / Research Article
RP-HPLC and UV Spectrophotometric Analysis of Paracetamol, Ibuprofen, and Caffeine in Solid Pharmaceutical Dosage Forms by Derivative, Fourier, and Wavelet Transforms: A Comparison Study Table 2 Assay results for the determination of PA, IB, and CA in solid pharmaceutical dosage forms.
% Of label claim (mean ± SD, n = 6) Method Bidi-Ipalvic Ibu-Acetalvic Glotasic PA IB CA PA IB CA PA IB CA RP-HPLC 100.9 ± 1.9 100.4 ± 2.0 100.5 ± 1.9 101.2 ± 1.9 100.6 ± 2.5 102.5 ± 1.9 101.6 ± 2.5 100.1 ± 2.6 100.9 ± 2.7 Derivative transform Single divisor 100.0 ± 1.7 99.9 ± 2.1 100.9 ± 1.9 99.9 ± 2.1 98.5 ± 2.6 102.7 ± 2.6 100.9 ± 2.4 98.8 ± 2.7 100.5 ± 1.8 Double divisor 101.3 ± 2.5 99.7 ± 2.4 101.1 ± 1.7 101.1 ± 2.4 101.1 ± 2.4 99.7 ± 2.7 100.6 ± 2.6 100.3 ± 1.9 100.9 ± 1.9 Successive divisor 100.4 ± 1.7 99.6 ± 2.1 100.2 ± 2.3 100.9 ± 2.4 101.7 ± 1.9 101.1 ± 2.5 101.9 ± 2.4 100.6 ± 2.5 99.2 + 2.6 Fourier transform Double divisor 100.7 ± 2.1 — — 99.9 ± 2.5 — — 100.4 ± 2.4 — — Wavelet transform Single divisor 101.3 ± 1.5 100.0 ± 1.4 100.6 ± 1.6 99.6 ± 2.0 101.2 ± 2.5 99.9 ± 2.3 98.8 ± 2.0 100.2 ± 2.1 100.8 ± 2.1 Double divisor 100.1 ± 2.0 100.4 ± 1.8 — 101.9 ± 2.6 99.4 ± 2.3 — 100.6 ± 2.0 100.3 ± 2.2 — Successive divisor 101.5 ± 2.1 100.7 ± 1.8 100.2 ± 2.4 101.5 ± 2.5 99.9 ± 2.4 99.4 ± 2.5 99.2 ± 2.2 101.2 ± 2.0 101.2 ± 2.5