RP-HPLC and UV Spectrophotometric Analysis of Paracetamol, Ibuprofen, and Caffeine in Solid Pharmaceutical Dosage Forms by Derivative, Fourier, and Wavelet Transforms: A Comparison Study

Table 3

Statistical analysis at the significance level 5% for spectrophotometric and liquid chromatographic determination of PA, IB, and CA in three commercial pharmaceutical formulations.

One-way ANOVA test
Source of variation	Compound		Between-groups	Within-groups	Total
Sum of squares	PA	I	13.770	153.55	167.32
		II	30.000	214.00	244.00
		III	47.640	215.65	263.29
	IB	I	6.000	135.10	141.10
		II	46.183	198.40	244.58
		III	18.891	185.80	204.69
	CA	I	9.530	118.60	128.13
		II	63.170	177.25	240.42
		III	15.290	157.80	173.09
Degree of freedom	PA		7	40	47
	IB		6	35	41
	CA		5	30	35
Calculated F value	PA	I	0.512
		II	0.801
		III	1.262
	IB	I	0.259
		II	1.358
		III	0.593
	CA	I	0.482
		II	2.138
		III	0.581
Tabulated F value	PA		2.249
	IB		2.372
	CA		2.534
Bartlett test
Calculated χ^2 value	PA	I	1.662
		II	0.859
		III	0.615
	IB	I	1.513
		II	0.544
		III	1.042
	CA	I	1.215
		II	0.677
		III	1.334
Tabulated χ^2 value (degree of freedom)	PA		14.067 (7)
	IB		12.592 (6)
	CA		11.070 (5)

I, Bidi-Ipalvic; II, Ibu-Acetalvic; III, Glotasic