Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shugan-San

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Botanical name</td><td class="align_center">Herbal name</td><td class="align_center">Chinese name</td><td class="align_center">Acquire from</td><td class="align_center">Ratio (%)</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left"><i>Bupleurum</i></td><td class="align_center">Bupleuri radix</td><td class="align_center">Chai-hu</td><td class="align_center">Root</td><td class="align_center">17.14</td></tr><tr><td class="align_left"><i>Glycyrrhiza glabra</i> L.</td><td class="align_center">Glycyrrhizae radix et rhizoma</td><td class="align_center">Zhi-gan-cao</td><td class="align_center">Root and rhizome</td><td class="align_center">8.56</td></tr><tr><td class="align_left"><i>Paeonia lactiflora</i> Pall.</td><td class="align_center">Paeoniae radix alba</td><td class="align_center">Bai-shao</td><td class="align_center">Root</td><td class="align_center">14.29</td></tr><tr><td class="align_left"><i>Citrus reticulata</i> Blanco</td><td class="align_center">Citri reticulatae pericarpium</td><td class="align_center">Chen-pi</td><td class="align_center">Pericarp</td><td class="align_center">17.14</td></tr><tr><td class="align_left"><i>Ligusticum chuanxiong</i> Hort.</td><td class="align_center">Chuanxiong rhizoma</td><td class="align_center">Chuan-xiong</td><td class="align_center">Rhizome</td><td class="align_center">14.29</td></tr><tr><td class="align_left"><i>Citrus aurantium</i> L.</td><td class="align_center">Aurantii fructus</td><td class="align_center">Zhi-qiao</td><td class="align_center">Fruit</td><td class="align_center">14.29</td></tr><tr><td class="align_left"><i>Cyperus rotundus</i> L.</td><td class="align_center">Cyperi rhizoma</td><td class="align_center">Xiang-fu</td><td class="align_center">Rhizome</td><td class="align_center">14.29</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The information of components in chaihu-shugan-san (CHSGS).</div>

Journal of Analytical Methods in Chemistry

tab1

Table 1

Table 1: Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shugan-San 

Table 1 | Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shugan-San 