Simultaneous Determination of Five Components of Chaihu-Shugan-San in Beagle Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Dose of Chaihu-Shugan-San

Table 3

Main analytical parameters of all analytes.

Analytes	Parent ion (m/z)	Product ion for quantification (m/z)	DP^a (V)	CE^b (eV)
Neohesperidin	609	301	−138	−65
Hesperidin	609	301	−115	−37
Naringin	579	271	−151	−49
Paeoniflorin	525	449	−66	−20
Liquiritin	417	254	−90	−28

DP, declustering potential; CE, collision energy. ^aDeclustering potential. ^bCollision energy.