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Journal of Analytical Methods in Chemistry
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Journal of Analytical Methods in Chemistry
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2020
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Article
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Tab 3
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Research Article
LC-MS/MS Method for Rapid Quantification of Progesterone in Rabbit Plasma and Its Application in a Pharmacokinetic Study of the Transdermal Formulation
Table 3
Pharmacokinetic parameters of progesterone on rabbit models.
Parameter
Eutectic-hydrogel system (±SD)
Reference drug formulation (±SD)
C
max
(ng/mL)
11.1 ± 0.66
8.49 ± 3.32
T
max
(h)
6.67 ± 0.58
6.33 ± 0.58
AUC
0−10 h
(ng.h/mL)
69.0 ± 6.49
46.5 ± 21.9