Selective Consecutive Determination of Desloratadine and Montelukast Sodium in Their Pure and Binary Dosage Form Based on Pencil Graphite Electrochemical Sensors

Table 5

Determination of DES and MON in pharmaceutical preparations by the constructed sensors and reported methods.

Commercial name	Composition	Amount found, mg^a	R% ± SD	t value^b	F value^c
Sensor 1 DES.RNK
Aerius	Desloratadine, 5 mg	4.980	99.60 ± 1.80	1.77	1.41
Azmalir	Montelukast sodium, 10 mg	—	—	—	—
Desolate-M	Desloratadine, 5 mg	4.993	99.87 ± 1.22	0.89	1.55
	Montelukast sodium, 10 mg	—	—	—	—
Sensor 2 MON.Cd.
Aerius	Desloratadine, 5 mg	—	—	—	—
Azmalir	Montelukast sodium, 10 mg	9.990	99.90 ± 0.85	0.30	2.34
Desolate-M	Desloratadine, 5 mg	—	—	—	—
	Montelukast sodium, 10 mg	9.916	99.16 ± 0.61	.0.92	1.00
Sensor 3 combined sensor
Aerius	Desloratadine, 5 mg	4.990	99.80 ± 1.60	1.04	1.11
Azmalir	Montelukast sodium, 10 mg	9.960	99.60 ± 1.15	0.60	1.27
Desolate-M	Desloratadine, 5 mg	5.020	100.40 ± 1.05	0.76	0.52
	Montelukast sodium, 10 mg	9.920	99.20 ± 0.92	0.83	2.27

^aAverage of 3 replicates; ^bt critical 4.302 (0.05); ^cf critical 19 (0.05); n = 3.