Development and Validation of Ecofriendly HPLC-MS Method for Quantitative Assay of Amoxicillin, Dicloxacillin, and Their Official Impurity in Pure and Dosage Forms

Table 2

Determination of AMOX and DIC in Miclox® capsules (Batch no. 001011) by the proposed HPLC/MS method and application of standard addition technique.

AMOX				DIC
Taken (µg mL^−1)	Found % ± SD	Pure added (µg mL^−1)	Recovery %	Taken (µg mL^−1)	Found % ± SD	Pure added (µg mL^−1)	Recovery %
10.00	99.63 ± 1.237	6.00	101.14	10.00	102.65 ± 1.297	5.00	97.94
		10.00	99.30			10.00	100.75
		12.00	102.55			15.00	97.43
Mean ± SD			100.99 ± 1.632	Mean ± SD			98.71 ± 1.788

Average of 6 determinations.