Research Article
Determination of Pharmaceutical Residues by UPLC-MS/MS Method: Validation and Application on Surface Water and Hospital Wastewater
Table 1
Operating conditions for target compounds in MS/MS mode in Waters Xevo-TQD mass spectrometer.
| No. | Compounds | RT (min) | Ratio TQ/TC | Precursor ion | Product ions | Cone (V) | Collision energy (eV) |
| 1 | PARA | 2.87 | 8.6 | 151.9 | 92.0 | 30 | 22 | 109.9 | 18 | 2 | PARA-D4 | 2.87 | — | 156.0 | 114 | 30 | 15 | 3 | TRIM | 3.13 | 1.6 | 291.0 | 229.9 | 28 | 24 | 260.9 | 24 | 4 | OFLO | 3.14 | 2.5 | 362.3 | 261.3 | 25 | 20 | 318.3 | 22 | 5 | OFLO-D3 | 3.14 | — | 365.0 | 321.1 | 55 | 20 | 6 | CIPRO | 3.15 | 11.6 | 332.1 | 288.1 | 42 | 18 | 314.1 | 22 | 7 | SULFA | 3.52 | 1.5 | 253.9 | 92.0 | 34 | 26 | 156.9 | 16 | 8 | SULFA–13C6 | 3.52 | — | 260.0 | 98.1 | 38 | 28 | 9 | CARBA | 3.81 | 1.2 | 236.9 | 178.9 | 42 | 34 | 193.6 | 36 | 10 | KETO | 4.11 | — | 254.9 | 209.1 | 36 | 12 |
|
|