Research Article
Determination of Pharmaceutical Residues by UPLC-MS/MS Method: Validation and Application on Surface Water and Hospital Wastewater
Table 1
Operating conditions for target compounds in MS/MS mode in Waters Xevo-TQD mass spectrometer.
| | No. | Compounds | RT (min) | Ratio
TQ/TC | Precursor ion | Product ions | Cone (V) | Collision energy (eV) |
| | 1 | PARA | 2.87 | 8.6 | 151.9 | 92.0 | 30 | 22 | | 109.9 | 18 | | 2 | PARA-D4 | 2.87 | — | 156.0 | 114 | 30 | 15 | | 3 | TRIM | 3.13 | 1.6 | 291.0 | 229.9 | 28 | 24 | | 260.9 | 24 | | 4 | OFLO | 3.14 | 2.5 | 362.3 | 261.3 | 25 | 20 | | 318.3 | 22 | | 5 | OFLO-D3 | 3.14 | — | 365.0 | 321.1 | 55 | 20 | | 6 | CIPRO | 3.15 | 11.6 | 332.1 | 288.1 | 42 | 18 | | 314.1 | 22 | | 7 | SULFA | 3.52 | 1.5 | 253.9 | 92.0 | 34 | 26 | | 156.9 | 16 | | 8 | SULFA–13C6 | 3.52 | — | 260.0 | 98.1 | 38 | 28 | | 9 | CARBA | 3.81 | 1.2 | 236.9 | 178.9 | 42 | 34 | | 193.6 | 36 | | 10 | KETO | 4.11 | — | 254.9 | 209.1 | 36 | 12 |
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