Sensitive Quantification of Liensinine Alkaloid Using a HPLC-MS/MS Method and Its Application in Microvolume Rat Plasma

Table 1

Liensinine and dauricine (IS) recoveries following extraction from rat plasma with three different solvents (n = 3).

Extraction solvent	Recovery (%)
	Liensinine (100 ng/mL)	Dauricine (IS) (100 ng/mL)
Methanol	68.68 ± 6.12	71.54 ± 8.20
Acetonitrile	72.19 ± 4.78	65.44 ± 6.10
MTBE	96.42 ± 3.22	95.57 ± 2.72