Sensitive Quantification of Liensinine Alkaloid Using a HPLC-MS/MS Method and Its Application in Microvolume Rat Plasma

Table 3

Matrix effect of liensinine at three QC levels.

Concentration (ng/mL)	Mean area ratio of postspiked and extracted (n = 5)	Mean area ratio of neat samples (n = 5)	Matrix effect (%)	RSD (%)
0.05 (LQC)	0.044622	0.045278	98.60	13.91
5.0 (MQC)	2.095712	2.247012	93.26	11.09
750 (HQC)	40.22435	37.62342	106.47	4.79