Research Article
Pharmacokinetics of 10-Hydroxy Mesaconitine in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Quadrupole Mass Spectrometry
Table 1
Accuracy, precision, matrix effect, and recovery of 10-hydroxy mesaconitine in rat plasma.
| | Concentration (ng/mL) | Accuracy (%) | Precision (%RSD) | Matrix effect (%) | Recovery (%) | | Intraday | Interday | Intraday | Interday |
| | 0.3 | 107.9 | 109.3 | 11.8 | 15.0 | 88.9 ± 7.8 | 93.0 ± 6.7 | | 0.8 | 103.1 | 103.2 | 9.2 | 8.3 | 94.2 ± 6.5 | 79.1 ± 5.3 | | 12 | 98.1 | 94.3 | 6.8 | 11.3 | 96.5 ± 4.5 | 87.7 ± 3.2 | | 50 | 97.2 | 102.1 | 4.5 | 6.1 | 98.1 ± 5.6 | 92.2 ± 3.4 |
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