Graphene Oxide-Gold Star Construct on Triangular Electrodes for Alzheimer’s Disease Identification

Figure 5

(a) Specific miRNA-137 detection. Experimented with control sequences of miRNA-21 (C-1) and single (C-2) and triple (C-3) base mismatched miRNA-137 sequences. Control sequences did not show any particular current response with complementary miRNA-137 compared with the specific hybridization (S). (b) Specific miRNA-137 detection. Experimented with mixed miRNA-137, miRNA-21, and serum. Mixing other molecules did not interfere the hybridization of miRNA-137 with complementary sequences and confirms the selective detection.

(a)

(b)