Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs

<div>Mean plasma concentration-time curves after oral administration of pioglitazone (2.6 mg/kg), omarigliptin (2.6 mg/kg), or pioglitazone (2.6 mg/kg) plus omarigliptin (2.6 mg/kg) (mean ± SD, <i>n</i> = 5).</div>

Journal of Analytical Methods in Chemistry

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Figure 5

Figure 5: Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs 

Figure 5 | Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs 