Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs

Table 1

Gradient elution procedure of the method.

Time (min)	Flow rate (mL/min)	A (%)	B (%)
0	0.3	80	20
0.1	0.3	80	20
0.3	0.3	20	80
2.0	0.3	20	80
2.1	0.3	20	20
3.0	Stop