Journal of Analytical Methods in Chemistry

Research Article

Establishment of Quality Evaluation Method for Yinqiao Powder: A Herbal Formula against COVID-19 in China

Table 3

Information of identified compounds in Yinqiao powder extract.


No	t_R (min)	Name	Formula	Ion mode	Theoretical (m/z)	Measured (m/z)	ppm	Fragments ion (m/z)	Peak area	Reference

1	0.64	Arginine	C₆H₁₄N₄O₂	[M + H]⁺	175.1190	175.1191	0.615	175.1191, 116.0709, 70.0659	9.26E + 08	[22]
2	0.72	Histidine	C₆H₉N₃O₂	[M + H]⁺	156.0768	156.0768	0.557	138.0549, 110.0717	3.29E + 07	–
3	0.72	Quinic acid	C₇H₁₂O₆	[M − H]⁻	191.0550	191.0552	1.180	127.0338, 85.0279	4.62E + 09	[23]
4	0.73	Proline	C₅H₉NO₂	[M + H]⁺	116.0706	116.0710	2.971	70.0656	5.20E + 09	[24]
5	0.73	Valine	C₅H₁₁NO₂	[M + H]⁺	118.0863	118.0866	3.090	100.1125, 72.0816	1.41E + 09	[22]
6	0.77	Glutamic acid	C₅H₉NO₄	[M + H]⁺	148.0604	148.0605	0.241	148.0605, 130.0500, 102.0554, 84.0451	8.99E + 07	[25]
7	1.02	Adenine	C₅H₅N₅	[M + H]⁺	136.0618	136.0619	0.869	119.0495, 91.0549	2.17E + 08	[26]
8	1.19	Isoleucine	C₆H₁₃NO₂	[M + H]⁺	132.1019	132.1021	1.096	132.1021, 86.0971	4.87E + 08	[25]
9	1.24	Tyrosine	C₉H₁₁NO₃	[M + H]⁺	182.0812	182.0813	0.935	165.0546, 136.0757, 123.0443	2.02E + 08	[24]
10	2.32	Phenylalanine	C₉H₁₁NO₂	[M + H]⁺	166.0863	166.0864	0.872	120.0810, 107.0496	7.23E + 07	[26]
11	5.51	Loganic acid	C₁₆H₂₄O₁₀	[M − H]⁻	375.1286	375.1299	3.403	213.0763, 151.0752, 125.0594	3.35E + 08	[23]
12	5.61	Neochlorogenic acid	C₁₆H₁₈O₉	[M − H]⁻	353.0867	353.0882	4.139	191.0553, 179.0340, 135.0438	8.78E + 08	[24]
13	5.69	Loganin	C₁₇H₂₆O₁₀	[M − H]⁻	389.1442	389.1458	3.923	345.1195, 227.0565, 183.0655, 139.0388	6.16E + 04	[27]
14	5.84	Forsythoside E	C₂₀H₃₀O₁₂	[M + H]⁺	463.1810	463.1809	−0.265	155.0704, 137.0596	1.72E + 07	[28]
15	5.92	Methyl cinnamate	C₁₀H₁₀O₂	[M + H]⁺	163.0754	163.0754	0.392	135.0442, 131.0493, 103.0547	1.69E + 07	[25]
16	7.10	Sweroside	C₁₆H₂₂O₉	[M − H]⁻	357.1180	357.1195	4.288	195.0661, 177.0545	5.87E + 05	[29]
17	7.31	Chlorogenic acid	C₁₆H₁₈O₉	[M − H]⁻	353.0867	353.0880	1.331	191.0553, 179.0431, 135.0438	1.38E + 09	[30]
18	7.80	Secoxyloganin	C₁₇H₂₄O₁₁	[M + H]⁺	405.1391	405.1392	0.054	243.0862, 225.0757, 165.0547, 151.0390	1.72E + 08	[23]
19	7.80	Scopoletin	C₁₀H₈O₄	[M + H]⁺	193.0495	193.0497	0.698	151.0396, 95.0497	8.68E + 07	[31]
20	7.97	Glycitin	C₂₂H₂₂O₁₀	[M + H]⁺	447.1286	447.1285	−0.142	285.0756, 270.0522, 242.0572	5.36E + 07	[32]
21	8.55	Rutin	C₂₇H₃₀O₁₆	[M + H]⁺	611.1607	611.1605	−0.329	465.1021, 303.0498	2.11E + 08	[23]
22	8.60	Liquiritigenin	C₁₅H₁₂O₄	[M + H]⁺	257.0808	257.0806	−1.032	147.0441, 137.0235, 119.0495	1.57E + 09	[33]
23	8.80	Isoquercitrin	C₂₁H₂₀O₁₂	[M + H]⁺	465.1028	465.1029	0.403	303.1497	4.34E + 07	[34]
24	8.80	Quercetin	C₁₅H₁₀O₇	[M + H]⁺	303.0499	303.0498	−0.426	153.0183, 137.0234	2.02E + 07	[34]
25	8.85	Cynaroside	C₂₁H₂₀O₁₁	[M + H]⁺	449.1078	449.1078	−0.040	287.0549, 241.0501	9.26E + 07	[23]
26	8.93	Genistin	C₂₁H₂₀O₁₀	[M + H]⁺	433.1129	433.1129	0.062	271.0598, 243.0652, 215.0702	8.08E + 07	[32]
27	9.13	Isoschaftoside	C₂₆H₂₈O₁₄	[M − H]⁻	563.1395	563.1411	2.802	383.0769, 353.0667, 297.0754	3.46E + 07	—
28	9.22	(+)-Pinoresinol	C₂₀H₂₂O₆	[M + H]⁺	359.1489	359.1487	−0.654	175.0755, 137.0598	2.20E + 07	[35]
29	9.23	Pµlegone	C₁₀H₁₆O	[M + H]⁺	153.1274	153.1274	0.119	109.1016, 81.0706	2.98E + 07	—
30	9.43	Daidzin	C₂₁H₂₀O₉	[M − H]⁻	415.1024	415.1041	1.741	253.0506, 135.0074	3.76E + 06	[32]
31	9.70	Hesperidin	C₂₈H₃₄O₁₅	[M + H]⁺	611.1970	611.1971	0.153	449.1436, 303.0860, 195.0288	1.64E + 08	[24]
32	9.83	Forsythoside I	C₂₉H₃₆O₁₅	[M − H]⁻	623.1970	623.1985	2.316	461.1655, 161.0233	2.53E + 09	[28]
33	10.00	Liquiritin	C₂₁H₂₂O₉	[M − H]⁻	417.1180	417.1195	3.527	255.0663, 135.0074, 119.0488	1.29E + 09	[33]
34	10.26	Forsythoside A	C₂₉H₃₆O₁₅	[M − H]⁻	623.1970	623.1985	2.316	461.1674, 161.0232	3.38E + 09	[28]
35	10.45	Lonicerin	C₂₇H₃₀O₁₅	[M − H]⁻	593.1501	593.1520	3.175	447.0936, 285.0406	3.51E + 07	[23]
36	10.51	Ononin	C₂₂H₂₂O₉	[M + H]⁺	431.1337	431.1335	−0.345	269.0806, 254.0572	2.98E + 08	[36]
37	10.60	Calceolarioside B	C₂₃H₂₆O₁₁	[M − H]⁻	477.1391	477.1407	3.253	161.0232, 133.0281	3.76E + 08	[36]
38	10.83	Kaempferol-3-O-rutinoside	C₂₇H₃₀O₁₅	[M − H]⁻	593.1501	593.1517	2.754	285.0407, 255.0298, 227.0345	3.70E + 07	[23]
39	10.91	Daidzein	C₁₅H₁₀O₄	[M + H]⁺	255.0652	255.0650	−0.766	227.0701, 199.0754, 137.0234	4.22E + 08	[32]
40	11.03	Isochlorogenic acid B	C₂₅H₂₄O₁₂	[M − H]⁻	515.1184	515.1180	−0.704	353.0877, 191.0552, 179.0340, 173.0445, 135.0437	6.27E + 08	[23]
41	11.09	Arctigenin	C₂₁H₂₄O₆	[M + H]⁺	373.1646	373.1642	−0.924	237.1121, 137.0597	2.93E + 09	[21]
42	11.17	Linarin	C₂₈H₃₂O₁₄	[M + H]⁺	593.1865	593.1863	−0.341	447.1284, 285.0756, 270.0523, 242.0571	7.65E + 07	—
43	11.22	Glycitein	C₁₆H₁₂O₅	[M + H]⁺	285.0758	285.0757	−0.351	270.0522, 242.0573	1.10E + 08	[32]
44	11.23	Isochlorogenic acid A	C₂₅H₂₄O₁₂	[M − H]⁻	515.1184	515.1189	0.966	353.0881, 191.0554, 179.0341, 173.0445, 135.0438	4.17E + 08	[23]
45	11.46	Azelaic acid	C₉H₁₆O₄	[M − H]⁻	187.0965	187.0968	1.681	143.1061, 125.0958, 97.0643	2.03E + 08	—
46	11.76	Isochlorogenic acid C	C₂₅H₂₄O₁₂	[M − H]⁻	515.1184	515.1171	−2.470	353.0869, 191.0557, 179.0340, 135.0439	8.75E + 08	[23]
47	11.79	Ferµlic acid	C₁₀H₁₀O₄	[M − H]⁻	193.0495	193.0499	2.045	178.0261, 161.0232, 133.0281	6.04E + 07	[37]
48	12.52	Isoliquiritin	C₂₁H₂₂O₉	[M − H]⁻	417.1180	417.1197	3.959	255.0661, 180.0054, 135.0074, 119.0487	2.29E + 08	[33]
49	12.67	Genistein	C₁₅H₁₀O₅	[M + H]⁺	271.0601	271.0600	−0.258	243.0649, 215.0704, 153.0183	7.06E + 07	[32]
50	13.04	Phillyrin	C₂₇H₃₄O₁₁	[M + HCOO]⁻	579.2072	579.2088	2.732	371.1496, 356.1265	1.03E + 09	[21]
51	13.32	Arctiin	C₂₇H₃₄O₁₁	[M + HCOO]⁻	579.2072	579.2087	2.525	371.1500, 356.1268	5.10E + 09	[21]
52	13.69	Luteolin	C₁₅H₁₀O₆	[M − H]⁻	285.0394	285.0406	4.194	151.0025, 133.0282, 107.0124	6.19E + 04	[33]
53	15.37	Matairesinol	C₂₀H₂₂O₆	[M − H]⁻	357.1332	357.1347	3.935	83.0122	2.13E + 08	—

: components with potential pharmacological effects; —: compared with Chinese medicine database.