Pharmacokinetic Study of Coadministration with Cefuroxime Sodium for Injection Influencing ReDuNing Injection-Derived Seven Phytochemicals and Nine Metabolites in Rats

Table 7

The related MS data of nine metabolites.

Analyte	tR (min)	m/z	(ms/ms)	Parent	Identification
M1	8.22	425.1075	249.0728, 231.0625, 199.0217	Geniposide	Glucuronidation
M2	13.16	427.1207	233.0789	Geniposide	Ring-opened in geniposide
M3	8.77	492.1520	330.1004, 312.0900	Geniposide	Cys conjugation
M4	13.14	225.0752	207.0651, 195.0594, 151.0755	Geniposide	Oxidation of geniposide aglycone
M5	12.23	209.0804	191.0705, 177.0543	Geniposide	Dehydration of geniposide aglycone
M6	11.04	197.0802	179.0703, 169.0858, 151.0753	Geniposide	Hydroxymethylene loss of geniposide aglycone
M7	11.42	229.0699	211.0601, 201.0748	Secoxyloganin	Hydrolysis of secoxyloganin aglycone
M8	13.12	451.1823	243.0860, 225.1123	Secoxyloganin	Hydroxylation and ethylation
M9	11.63	375.1275	357.1138, 347.1331, 195.0652	Secoxyloganin	Hydroxymethylene loss