Study of Saponin Components after Biotransformation of Dioscorea nipponica by Endophytic Fungi C39

Table 1

The OD value of different drug concentrations.

		0 (μg/mL)	7.8125 (μg/mL)	15.625 (μg/mL)	31.25 (μg/mL)	62.5 (μg/mL)	125 (μg/mL)	250 (μg/mL)
HepG2 cells	Crude drug	0.86 ± 0.03	0.81 ± 0.04	0.68 ± 0.12	0.61 ± 0.08	0.47 ± 0.03	0.15 ± 0.02	0.08 ± 0.01
	Control drug	0.85 ± 0.05	0.82 ± 0.07	0.70 ± 0.06	0.51 ± 0.07^#	0.33 ± 0.06^##	0.28 ± 0.06^##	0.16 ± 0.05^##
	Fermentation drug	0.89 ± 0.04	0.44 ± 0.09	0.26 ± 0.09	0.19 ± 0.05	0.10 ± 0.02	0.08 ± 0.01	0.08 ± 0.01
BGC823 cells	Crude drug	0.80 ± 0.05	0.79 ± 0.02	0.69 ± 0.04	0.56 ± 0.04	0.42 ± 0.05	0.28 ± 0.05	0.11 ± 0.02
	Control drug	0.85 ± 0.05	0.77 ± 0.04	0.61 ± 0.02^##	0.49 ± 0.02^##	0.37 ± 0.02^#	0.17 ± 0.03^##	0.09 ± 0.01
	Fermentation drug	0.83 ± 0.04	0.51 ± 0.02	0.38 ± 0.01	0.26 ± 0.02	0.11 ± 0.01	0.09 ± 0.01	0.09 ± 0.01
HeLa cells	Crude drug	0.93 ± 0.04	1.03 ± 0.03	0.84 ± 0.07	0.61 ± 0.03	0.56 ± 0.03	0.48 ± 0.05	0.11 ± 0.01
	Control drug	0.98 ± 0.03	0.98 ± 0.03^#	0.81 ± 0.05	0.65 ± 0.03^#	0.53 ± 0.02	0.49 ± 0.04	0.16 ± 0.02^##
	Fermentation drug	0.93 ± 0.03	0.88 ± 0.06	0.72 ± 0.06	0.51 ± 0.03	0.42 ± 0.06	0.17 ± 0.05	0.12 ± 0.03
A549 cells	Crude drug	0.37 ± 0.02	0.33 ± 0.03	0.24 ± 0.02	0.17 ± 0.01	0.16 ± 0.02	0.11 ± 0.01	0.11 ± 0.01
	Control drug	0.40 ± 0.03	0.34 ± 0.03	0.22 ± 0.03	0.15 ± 0.02^#	0.15 ± 0.02	0.12 ± 0.01	0.12 ± 0.01
	Fermentation drug	0.40 ± 0.03	0.20 ± 0.04	0.17 ± 0.02	0.13 ± 0.02	0.14 ± 0.01	0.11 ± 0.01	0.08 ± 0.01

Data are presented as mean ± SD (n = 6) and compared with fermentation drug group and and compared with the control drug group.