A Human Oral Fluid Assay for D- and L- Isomer Detection of Amphetamine and Methamphetamine Using Liquid-Liquid Extraction

Table 9

Matrix effects 10 different lots of oral fluid were fortified with QC material to a concentration of 7.5 ng/mL and the %CV determined of the analyte/IS area ratio.

Drug/Metabolite	Matrix comparison
	%CV Analyte/IS ratio
Amphetamine	3.39
Methamphetamine	4.60
D-amphetamine	1.59
L-amphetamine	2.35
D-methamphetamine	7.54
L-methamphetamine	3.09

Indicates combined D- and L-.