Measurement of Pharmacokinetics and Tissue Distribution of Four Compounds from <i>Nauclea officinalis</i> in Rat Plasma and Tissues through HPLC-MS/MS

<div>Typical chromatograms of four analyte and IS in rat plasma: (a) blank plasma samples, (b) blank plasma samples spiked with four analytes (LLOQ) and IS, (c) rat plasma samples at 0.5 h after oral administration the <i>Nauclea officinalis</i> extracts spiked with IS; (1) chlorogenic acid, (2) naucleactonin C, (3) khaephuoside A, (4) 3,4-dimethoxyphenyl-1-O-<i>β</i>-apiofuroseyl(1 ⟶ 2)-<i>β</i>-D-glucopyranoside, (5) chloramphenicol (IS).</div>

Journal of Analytical Methods in Chemistry

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Figure 2

Figure 2: Measurement of Pharmacokinetics and Tissue Distribution of Four Compounds from <i>Nauclea officinalis</i> in Rat Plasma and Tissues through HPLC-MS/MS 

Figure 2 | Measurement of Pharmacokinetics and Tissue Distribution of Four Compounds from Nauclea officinalis in Rat Plasma and Tissues through HPLC-MS/MS 