Research Article

Rapid Characterization and Action Mechanism of the Antidiabetic Effect of Diospyros lotus L Using UHPLC-Q-Exactive Orbitrap MS and Network Pharmacology

Table 1

The range of the parameters of the “drug-like soft” principle.

PropertyRangePropertyRange

MW100–600logP−3–6
HBA≤12HBD≤7
tPSA≤180Rotatable bonds≤11
Rigid bonds≤30Rings≤6
Max size system ring≤18Carbons3–35
Hetero atoms1–15H/C ratio0.1–1
Charges≤4Total charge−4–4