Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease
Table 2
Sample demographics by depression group.
No Depression
LOD
P value*
132
36
Age at CT scan (SD)
81.1 (6.1)
81.0 (7.0)
n.s.
Age at dementia onset (SD)
75.9 (6.9)
76.9 (6.7)
n.s.
Dementia duration, years (SD)
5.2 (4.2)
4.2 (3.5)
n.s.
% Female
63.6
63.9
n.s.
Education, years (SD)
7.5 (2.4)
7.4 (2.8)
n.s.
Monozygotic, (%)
33 (25.0)
15 (41.7)
0.05
Hypertension, (%)
113 (85.6)
30 (83.3)
n.s.
Diabetes, (%)
32 (24.2)
6 (16.7)
n.s.
Arrhythmia, (%)
25 (18.9)
8 (22.2)
n.s.
PAD, (%)
3 (2.3)
1 (2.8)
n.s.
CAD, (%)
41 (31.1)
16 (44.4)
0.13
TIA, (%)
14 (10.7)
0 (0.0)
0.04
Associations significant at are bolded. LOD: late-onset depression; PAD: peripheral artery disease; CAD: coronary artery disease; TIA: transient ischemic attack.
*Group comparisons by ANOVA for continuous variables and by chi-square for categorical variables.
