Fiber Tracts Anomalies in APPxPS1 Transgenic Mice Modeling Alzheimer's Disease
Summary of quantitative morphological analysis. The analysis was focused on the corpus callosum (left column) and on the anterior commissure (right column). Morphological data were collected in old and in young mice from PS1 and APPxPS1 genotypes. (a)-(b). Size of fiber tracts (pixels). (c)-(d). Relative optical densities (ROD) of neurofilament M145Kd (axons) immunostainings. (e)-(f). Relative optical densities of gold chloride (myelin) stainings. See text for details. All measures are illustrated by means + SEM in each experimental groups. *, **, ***.
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