Fiber Tracts Anomalies in APPxPS1 Transgenic Mice Modeling Alzheimer's Disease
Representative illustration of neurofilament immunostainings. Immunodetection of axonal neurofilaments is illustrated at the level of the corpus callosum (a) and anterior commissure (b) in both young and old PS1 and APPxPS1 transgenics. See text for details concerning age and genotype effects. Black arrow heads point to positive axonal enlarged varicosities in old APPxPS1 mice. Scale bars: 100 μm.
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