Fiber Tracts Anomalies in APPxPS1 Transgenic Mice Modeling Alzheimer's Disease
Representative illustration of myelin stains of fiber tracts. Myelin (gold chloride) stains are illustrated at the level of the corpus callosum (a) and anterior commissure (b) in both young and old PS1 and APPxPS1 transgenics. See text for details concerning age and genotype effects. Black arrow heads ((a) lower right photo) point to circular unstained areas corresponding to amyloid plaques in the corpus callosum of old APPxPS1 mice. Scale bars: 100 μm.
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