Genetic Risk Factors for Longitudinal Changes in Structural MRI in Former Organolead Workers

<table>Change in total brain, GM, and WM volumes by <i>APOE</i> genotype. The grey and black lines are estimated change in volumes (<svg height="11.2875" id="M41" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 71.762497 11.2875" width="71.762497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>% confidence interval) for the <i>APOE ε</i>3/<i>ε</i>3 and <i>APOE ε</i>3/<i>ε</i>4 + <i>ε</i>4/<i>ε</i>4 groups, respectively. The asterisk indicates that the estimated change for the <i>ε</i>3/<i>ε</i>4 + <i>ε</i>4/<i>ε</i>4 group is significantly different than for the <i>ε</i>3/<i>ε</i>3 group (<i>P</i> &lt; 0.05).</table>

Journal of Aging Research

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Figure 1

Figure 1: Genetic Risk Factors for Longitudinal Changes in Structural MRI in Former Organolead Workers 