Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats

Figure 4

Pro-NGF treatment resulted in observable degeneration of the cholinergic neurons stained for Choline Acetyl Transferase (ChAT; (b), (c)) when compared to age matched saline animals (a). Arrows in (b) point to neurons represented in (c) under higher magnification. Scale bar = 50 μm, 20x ((a) and (b)) and 40x (c).

(a)

(b)

(c)