Clinical Study
Cognitive Stimulation for Apathy in Probable Early-Stage Alzheimer's
Table 2
Variables and measurement.
| Cognition and Eligibility for study | Mini-Mental State examination (MMSE) [22] | The MMSE consists of 11 simple questions or tasks. Test-retest reliability . | Neuropsychiatric behaviors | Clinician administered Apathy Evaluation Scale (AES) [19] | The AES is an 18-item scale. Internal consistency has an alpha range of 0.86–0.94.Validity: differences found | Quality of life | Cornell-Brown QOL [24] | Interrater reliability (intraclass ) and internal consistency reliability (Cronbach alpha = 0.81). | Depression | The Patient Health Questionnaire [25] (PHQ-9) | Nine-item scale with PHQ-9 score ≥10 had a sensitivity of 88% and a specificity of 88% for major depression. | Executive function | Trail Making B [26] | Validity is high, especially when measuring attention and executive function |
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