Depressive Symptoms and Amygdala Volume in Elderly with Cerebral Small Vessel Disease: The RUN DMC Study

Table 3

The risk of LODS and EODS per decrease in amygdala volume, white matter lesion (WML), volume and lacunar infarcts.

	Patients with LODS; (𝑛=101)		Patients with EODS; (𝑛=108)
	OR	95% CI	OR	95% CI
Total amygdala volume*	1.77	1.02–3.08^†	0.95	0.56–1.61
Left amygdala volume*	2.92	1.22–7.01^†	0.98	0.41–2.30
Right amygdala volume*	1.53	0.59– 4.03	0.85	0.34–2.14
WML volume**	0.99	0.97–1.00	1.01	0.99–1.03
Lacunar infarcts***	1.32	0.78–2.23	0.80	0.46–1.39

Number represent odds ratio (OR), 95% confidence interval (CI), *adjusted for age, sex, WML, ICV volume, and presence of lacunar infarcts, **adjusted for age, sex, total amygdala volume, ICV, and presence of lacunar infarcts, ***adjusted for age, sex, ICV, WML, and amygdala volume, ^†𝑃<0.05.