Review Article
Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine
Table 2
Potential mediators of personality-longevity associations.
| Behavioral | Biological |
| Alcohol use | Cortisol, markers of HPA Axis function | Cigarette smoking and tobacco use | Epinephrine/Norepinephrine, markers of SAM Axis Function | Physical activity and exercise | Inflammatory Markers | BMI | Adaptive Immune Markers (Natural Killer Cells, White Blood Cell Count) | Illicit drug use; abuse of prescription medications | Markers of oxidative stress | Specific eating habits | Lipids and sclerotic activity | Accidents | Neurodegeneration associated with HPA axis dysregulation | Sexual risk behavior | Markers of metabolic dysregulation such as insulin resistance | Health risk perception and evaluation | Genetic Markers of Disease and Longevity | Health service use | Telomere shortening and other markers of impaired genetic replication | Health care adherence; communication with health care providers; trust in health care delivery system | Mechanisms of pain and somatic sensitivity | Sleep behavior; dental hygiene | | Complementary and Alternative Medicine Use | | Health beliefs and somatic sensitivity | | Recruitment of social support; informal help-seeking | |
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