Journal of Aging Research / 2011 / Article / Tab 1

Review Article

Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging

Table 1

List of major profiling studies of the mitochondrial proteome.

Proteomic studiesMitochondrial protein identificationReference

Proteomic analysis of human placentaFirst comprehensive cataloguing of the mitochondrial proteome, which resulted in the identification of 46 distinct proteinsRabilloud et al. [70]
Analysis of human and mouse heartIdentification of 680 human mitochondrial proteins and 940 mouse mitochondrial proteins in heart muscleTaylor et al. [71], Gaucher et al. [72], Zhang et al. [73]
Proteomic profiling of mouse and rat liverIdentification of 182 mouse proteins and 192 rat proteins that are associated with liver mitochondriada Cruz et al. [74], Fountoulakis et al. [75]
Proteomic profiling of human skeletal muscleIdentification of 823 mitochondrial proteins in human vastus lateralis muscleLefort et al. [76]
Proteomic profiling of brown and white adipose cell linesIdentification of 723 mitochondrial proteins in brown adipose cell line and 1,198 mitochondrial proteins in white adipose cell lineForner et al. [77]
Comparative studies for the establishment of the mammalian mitochondrial proteome from various tissuesIdentification of tissue-specific expression patterns of mouse and rat mitochondrial proteins from liver, skeletal muscle, kidney, brain, heart, and various other organs. The most comprehensive comparative study established the mitochondrial protein complement in 14 different tissuesMootha et al. [67], Forner et al. [68], Reifschneider et al. [69], Pagliarini et al. [78]

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