Multiple Comorbid Conditions among Middle-Aged and Elderly Hemophilia Patients: Prevalence Estimates and Implications for Future Care
Table 1
Diagnostic criteria for defining co-morbid conditions.
Condition
Criteria‡
Human immunodeficiency virus
HIV-1 PCR quantification
On drug therapy (HAART)
Hepatitis C virus
HCV RNA
On or received drug therapy
Overweight/obesity
Based on their BMI† score, patients were categorized as overweight or obese based on the following:
Overweight: 25.0–29.9
Obesity: 30.0 and above
Cardiovascular disease
Echocardiogram findings
Electrocardiogram findings
On drug therapy
Cardiologist notes
Hypertension
≥130 mmHg systolic blood pressure
≥85 mmHg diastolic blood pressure
Primary care physician notes
On drug therapy for elevated blood pressure
Hypercholesterolemia
Lipid profile
On drug therapy for high lipids
Primary care physician notes
Chronic arthropathy
Physical findings
Radiographic findings
Hepatitis B virus
Hepatitis B surface antigen detected for more than 6 months
Diabetes
Primary care physician notes
On drug therapy
Renal disease
Patient is on dialysis
Pathology results from biopsy
Estimation of glomerular filtration rate (GFR)
Nephrologist notes
Depression
On drug therapy
Psychiatry notes
Respiratory diseases
Positive radiographic findings
Primary care physician notes
On drug therapy or continuous positive airway pressure (CPAP) therapy
Gastrointestinal diseases
Gastroenterologist notes
Endoscopy findings
On drug therapy
Thyroid disease
On drug therapy
Neurological disease
Neurologist or primary care physician notes
On drug therapy
Cancer
Oncologist notes
Pathology reports
Radiographic findings
‡Patient was considered to have a specific comorbidity if any of the criteria for that condition was indicated in their chart. †National Center for Health Statistics. Health, United States, 2009, Hyattsville, MD, 2010.
