Journal of Aging Research / 2011 / Article / Tab 3

Research Article

Multiple Comorbid Conditions among Middle-Aged and Elderly Hemophilia Patients: Prevalence Estimates and Implications for Future Care

Table 3

Prevalence estimates and 95% confidence intervals of co-morbid conditions among hemophilia patients compared to the general US male population, by selected characteristics.

ConditionHemophilia A and B patients ( )Prevalence in general US male population
%95% CI%

Total number of co-morbid conditions††
1-21625.414.35, 36.45
3-42234.922.82, 47.02
5-61727.015.72, 38.25
≥7812.74.24, 21.15

HIV positive1625.414.35, 36.45 –49 years: 0.74
40–49 years1137.919.15, 56.71

HCV positive4977.867.22, 88.33 –49 years: ~ 6
50–59: 1.6
≥60 years: 0.9
40–49 years2172.455.11, 89.72
50–59 years1583.364.26, 99.02
≥60 years1381.359.77, 99.03

BMI
Normal (18.5–24.9)2234.922.82, 47.02
Overweight (25.0–29.9)2539.727.26, 52.10
Obese (≥30)1625.414.34, 36.45

BMI ≥25.0 25.0
40–59 years: 77.8
≥60 years: 78.4
40–59 years3370.256.64, 83.79
≥60 years850.022.48, 77.52

BMI ≥30.0 30.0
40–59 years: 34.3
≥60 years: 37.1
40–59 years1327.714.38, 40.93
≥60 years318.8

BMI ≥35.0 35.0
40–59 years: 11.6
≥60 years: 11.6
40–59 years612.82.8, 22.67
≥60 years16.3

BMI ≥40.0 40.0
40–59 years: 4.2
≥60 years: 4.2
40–59 years24.3
≥60 years

Cardiovascular disease†††3047.634.94, 60.30 years: 39.1
≥60 years: 71.3
40–59 years1940.425.86, 54.99
≥60 years1168.843.24, 94.26

Hypertension2946.033.38, 58.69
40–44 years646.214.80, 77.51 years: 36.2
55–64 years: 50.2
65–74 years: 64.1
≥75 years: 65.0
45–54 years730.410.09, 50.78
55–64 years853.324.74, 81.93
65–74 years660.023.06, 96.94
≥75 years2100

Hypercholesterolemia1015.96.60, 25.15
45–54 years417.40.63, 34.15 years: 36.2
55–64 years: 50.2
65–74 years: 64.1
≥75 years: 65.0
55–64 years213.3
65–74 years220.0
≥75 years150.0

Chronic arthropathy3352.439.70, 65.06
40–59 years2246.832.00, 61.62
≥60 years1168.843.24, 94.26
HBV positive46.40.16, 12.54

Diabetes914.35.40, 23.17

Renal disease57.91.07, 14.80

Depression57.91.07, 14.80

Respiratory disease711.13.13, 19.09

Gastrointestinal disease34.8

Thyroid disease46.40.16, 12.54

Neurological disease34.8

Cancer1015.96.60, 25.15
Hepatocellular carcinoma770.0
Non-Hodgkin’s lymphoma110.0
Lung cancer110.0
Leukemia110.0

CI: Confidence interval,
Prevalence estimates reported when data were available:
asee [16].
bsee [17].
csee [18].
dsee [19].
esee [20].
††Number of conditions excluding hemophilia disease.
†††Includes patients with cardiovascular disease, hypertension, and stroke.

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