Review Article

Apathy as Marker of Frail Status

Figure 1

Schematic representation of basal ganglia circuit. In this scheme the nucleus accumbens (NAcc) is an interface through which limbic (glutamatergic) structures influence motor activity, in a way that limbic structures can influence behavior, under control of meso-limbic (dopaminergic structures) system (Ventral Tegmental Area neurons).
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