Research Article
Association of Social Engagement with Brain Volumes Assessed by Structural MRI
Table 2
Adjusted associations between social engagement (independent variable) and ROI volumes (dependent variables).
| ROI | Mean volume (cc) | Social engagement standardized coefficient | value |
| Total brain volume | 1137.96 | 0.037 | 0.011 | Total gray matter (GM) | 534.14 | 0.072 | 0.007 | Total white matter (WM) | 603.82 | 0.001 | 0.975 | Gray matter lobes | | | | Frontal GM | 134.85 | 0.037 | 0.273 | Temporal GM | 96.58 | 0.083 | 0.009 | Parietal GM | 65.40 | 0.068 | 0.081 | Occipital GM | 45.56 | 0.076 | 0.048 | White matter lobes | | | | Frontal WM | 201.47 | 0.008 | 0.761 | Temporal WM | 119.03 | 0.021 | 0.501 | Parietal WM | 106.08 | 0.026 | 0.456 | Occipital WM | 58.22 | 0.007 | 0.869 | Smaller structures | | | | Cerebellum | 119.63 |
−0.013
| 0.763 | Medial structures | 80.63 | 0.047 | 0.135 | Cingulate gyrus | 21.02 | 0.045 | 0.269 | Insula | 13.94 | 0.008 | 0.865 | Corpus callosum | 11.89 | 0.127 | 0.004 | Internal capsule | 9.85 | 0.026 | 0.520 | Hippocampus | 7.42 |
−0.004
| 0.923 | Amygdala | 2.43 | 0.037 | 0.453 | Entorhinal cortex | 2.37 |
−0.016
| 0.756 |
|
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From models adjusted for age, education, intracranial volume, race/ethnicity, hypertension, diabetes, handedness, and control status. Bold: .
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