Effect of Caloric Restriction on Hepatic Sinusoidal System and Stellate Cells in Mice
Figure 1
Representative intravital fluorescence microscopic images of the retinyl ester auto-fluorescence ((a) and (b)) and sinusoidal architecture ((c) and (d)). Liver from calorically restricted mice (a) shows diminished spots and intensity of vitamin A auto-fluorescence compared with control liver (b); the calorically restricted liver also has homogenous sinusoids (c) while the unrestricted liver contains more torturous sinusoids (d). Animal age is 14 months. The magnification is 20x ((a), (b)) or 100x ((c), (d)).
