Research Article

Intramuscular Olanzapine in the Management of Behavioral and Psychological Symptoms in Hospitalized Older Adults: A Retrospective Descriptive Study

Table 1

Baseline demographic characteristics of older patients prescribed olanzapine.

Received olanzapineNo olanzapineAll cases

Age, mean (years)79.679.079.3
Female19 (55.9%)26 (51%)45 (52.9%)
Admission from
 Home18 (52.9%)41 (80.4%)59 (69.4%)
 Another hospital4 (11.8%)2 (3.9%)6 (7.1%)
 Retirement/LTC facilities12 (35.3%)8 (15.7%)20 (23.5%)
Discharge destination
 Home10 (29.4%)20 (39.2%)30 (35.3%)
 Another institution6 (17.6%)6 (11.8%)12 (14.1%)
 Retirement/LTC facilities18 (53.0%)23 (45.1%)41 (48.2%)
 Death02 (3.9%)2 (2.4%)
Types of patients
 Psychiatry22 (64.7%)29 (56.9%)51 (60.0%)
 General medicine12 (35.3%)21 (41.2%)31 (36.4%)
 Surgery02 (3.9%)2 (2.4%)
 Intensive care unit01 (2.0%)1 (1.2%)
Comorbidities
 Cognitive impairment/dementia21 (61.8%)33 (64.7%)54 (63.5%)
 Delirium9 (26.5%)16 (31.4%)25 (29.4%)
 Psychiatric disorders19 (55.9%)24 (47.1%)43 (50.6%)
 Neurological disorder5 (14.7%) 6 (11.8%)11 (12.9%)
 Insomnia3 (8.8%)5 (9.8%)8 (9.4%)
 Pain01 (1.9%)1 (1.2%)
 Acute infection7 (20.6%)13 (25.5%)20 (23.5%)
 Other6 (17.6%)5 (9.8%)11 (12.9%)
Number of comorbidities
 117 (50.0%)25 (49.0%)42 (49.4%)
 211 (32.3%)10 (19.6%)21 (24.7%)
 32 (5.9%)10 (19.6%)12 (14.1%)
4 4 (11.8%)6 (11.8%)10 (11.8%)
Concurrent psychotropic medications
 Other antipsychotics29 (85.3%)41 (80.4%)70 (83.4%)
 Benzodiazepines11 (32.4%)10 (19.6%)21 (24.7%)
 Antidepressants18 (52.9%)18 (35.3%)36 (42.4%)
 Antidementia medications7 (20.6%)14 (27.4%)21 (24.7%)
 Mood stabilizer4 (11.8%)4 (7.8%)8 (9.4%)
 Pain medications01 (1.96%)1 (1.2%)
 Other sedatives02 (3.9%)2 (2.4%)
Number of psychotropic medications (nonantipsychotics)
 08 (23.5%)13 (25.5%)21 (24.7%)
 19 (26.5%)20 (39.2%)29 (34.1%)
 214 (41.2%)17 (33.3%)31 (36.4%)
 31 (2.9%)1 (2.0%)2 (2.4%)
 42 (5.9%)02 (2.4%)

LTC: long-term care.