Age-Dependent Loss of Mitochondrial Function in Epithelial Tissue Can Be Reversed by Coenzyme Q₁₀

Figure 2

Mitochondrial respiration (a) and ATP production (b) in epithelial tissue depend on donor age. 16 hours prior to measurement, purified biopsies were stored overnight at 4°C in Dispase II. On the next day, the mitochondrial respiration of the separated epidermis was analyzed with an XF analyzer (n = 23, linear regression with 95% confidence interval, R² mitochondrial respiration = 0.5487/, ATP production = 0.2945/, deviation from zero = significant).

(a)

(b)