Circulating miR-34a and Bone Mineral Density of Brazilian Very-Old Adults
Table 2
Correlational and linear regression analyses of circulating levels of miRNAs with common clinical, anthropometric, and metabolic features of the very-old subjects investigated.
Traits
Log-transformed levels of microRNAs
miR1
miR21
miR34a
miR92a
miR100
miR126
miR130a
miR146a
miR155
miR221
Age
−0.02; 0.922
−0.22; 0.166
0.07; 0.663
−0.16; 0.311
−0.13; 0.412
0.05; 0.752
0.06; 0.698
−0.01; 0.937
−0.20; 0.208
−0.01; 0.944
Sex§
0.29; 0.059
−0.21; 0.631
0.16; 0.603
0.06; 0.945
0.11; 0.763
0.26; 0.408
0.28; 0.642
−0.21; 0.631
0.06; 0.926
−0.57; 0.260
Body fat
0.14; 0.385
0.18; 0.256
−0.07; 0.687
0.15; 0.363
0.16; 0.309
−0.15; 0.366
0.21; 0.185
0.04; 0.830
0.19; 0.244
0.23; 0.147
T2DM§
0.43; 0.262
−0.41; 0.326
−0.56; 0.070
0.54; 0.556
0.03; 0.935
−0.20; 0.503
−0.29; 0.623
0.96; 0.027
−0.53; 0.424
0.06; 0.907
Hypertension§
0.16; 0.516
−0.08; 0.771
−0.01; 0.954
−0.05; 0.933
0.26; 0.278
−0.17; 0.385
0.08; 0.840
0.06; 0.830
0.63; 0.145
−0.16; 0.600
Physical activity§
0.13; 0.715
0.12; 0.749
−0.10; 0.727
−0.74; 0.382
0.41; 0.223
0.08; 0.776
−0.82; 0.138
0.61; 0.117
0.66; 0.284
0.10; 0.819
Metabolic syndrome§
−0.14; 0.642
−0.17; 0.613
−0.07; 0.767
1.41; 0.069
−0.04; 0.907
−0.24; 0.324
0.38; 0.434
−0.04; 0.907
−0.42; 0.439
−0.20; 0.613
Log C-RP
0.05; 0.770
−0.06; 0.710
0.30; 0.057
0.09; 0.581
0.11; 0.509
−0.02; 0.919
0.16; 0.320
0.13; 0.432
−0.06; 0.711
0.09; 0.577
Serum creatinine
−0.07; 0.659
−0.04; 0.826
−0.08; 0.642
−0.04; 0.815
−0.22; 0.181
−0.01; 0.992
0.05; 0.771
0.02; 0.896
−0.01; 0.940
−0.02; 0.886
Creatinine clearance
−0.01; 0.983
0.01; 0.978
0.00; 0.998
0.02; 0.902
0.16; 0.315
−0.06; 0.734
−0.13; 0.436
−0.12; 0.474
0.02; 0.919
−0.05; 0.764
The Pearson correlation test (two continuous) or a Linear Regression Model§ (one continuous and one categorical) were used to test relationships between variables. Data are expressed as correlation index and significance level (r; ) or as beta coefficient and significance level (β; ) for correlational and regression analyses, respectively. T2DM = type 2 diabetes mellitus. C-RP = C-reactive protein. Log = logarithmically transformed.
