Circulating miR-34a and Bone Mineral Density of Brazilian Very-Old Adults
Table 3
Linear regression analyses of circulating levels of microRNAs with mineral content in coronary and bone territories of the very-old subjects investigated.
Log-transformed levels of microRNAs
Log Agatston score
BMD§
T scores§
LS
FH
FN
LS
FH
FN
miR-1-3p
0.26; 0.320
−0.17; 0.247
−0.16; 0.193
−0.07; 0.658
−0.19; 0.237
−0.21; 0.143
−0.09; 0.565
miR-21-5p
−0.06; 0.858
0.09; 0.541
−0.12; 0.334
−0.02; 0.868
0.08; 0.604
−0.16; 0.261
0.02; 0.926
miR-34a-5p
−0.09; 0.780
−0.05; 0.735
−0.36; 0.001
−0.22; 0.130
−0.05; 0.745
−0.43; 0.001
−0.24; 0.131
miR-92a-3p
−0.42; 0.923
0.05; 0.734
−0.13; 0.294
−0.08; 0.583
0.03; 0.829
−0.17; 0.228
−0.05; 0.757
miR-100-5p
−0.04; 0.867
−0.04; 0.793
0.20; 0.092
0.26; 0.073
−0.06; 0.694
0.23; 0.093
0.25; 0.109
miR-126-3p
0.44; 0.147
0.05; 0.753
−0.27; 0.022
−0.15; 0.294
0.05; 0.771
−0.31; 0.022
−0.13; 0.409
miR-130a-3p
−0.81; 0.208
0.09; 0.545
−0.21; 0.078
−0.10; 0.505
0.10; 0.548
−0.26; 0.059
−0.07; 0.644
miR-146a-5p
0.13; 0.764
−0.01; 0.954
−0.25; 0.032
−0.16; 0.270
−0.01; 0.956
−0.30; 0.027
−0.13; 0.393
miR-155-5p
0.09; 0.787
0.14; 0.328
−0.14; 0.248
−0.17; 0.232
0.14; 0.387
−0.18; 0.189
−0.12; 0.449
miR-221-3p
1.00; 0.087
0.05; 0.735
−0.22; 0.062
−0.07; 0.618
0.05; 0.769
−0.27; 0.045
−0.06; 0.700
A Linear Regression Model was used, with adjustment§ to sex and to physical activity practicing. Data are expressed as beta coefficient and significance level (β; ). BMD = bone mineral density; LS–lumbarsacral; FH = femural Head; FN = femural Neck; Log = logarithmically transformed.
